If you attempt to run SQL queries in a SQL worksheet and that query includes ampersands then SQL Developer will prompt you for bind variable values. It assumes anything starting with an ampersand must be a bind variable.
For example the query below :
SELECT * FROM TBL_COLOURS WHERE colour = 'Red&Blue';
SELECT * FROM TBL_COLOURS WHERE colour = 'Red' || '&' || 'Blue';
SET DEFINE OFF;